Hemin-induced DEGs in Lung, Kidney of WT and hepatic SR-BI KO mice
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ABSTRACT: Acute hemolysis can deplete haptoglobin and hemopexin, leaving toxic free heme insufficiently controlled. Here, the authors show that scavenger receptor BI (SR-BI) mediates hepatic uptake of free heme and is essential for protection against heme-induced injury and death. Here we examined gene expression post hemin injections
INSTRUMENT(S): Illumina NovaSeq 6000
ORGANISM(S): Mus musculus
SUBMITTER: Jianyao Xue
PROVIDER: E-MTAB-17338 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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