Unknown,Transcriptomics,Genomics,Proteomics

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ChIP-seq of definitive endoderm cells derived in vitro from human embryonic stem cells in order to study the role of transcription factor GATA6 in human pancreas development

ABSTRACT: Mutant GATA6 hPSCs were obtained by TALEN genome editing or re-programmed from patient fibroblasts. Along with wild-type H9 cells, these GATA6 mutant cell lines were differentiated into SOX17+/CXCR4+ endodermal cells (day 3). The purpose of this work was to study the role of GATA6 in the development of the human pancreas at a molecular level.

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Homo sapiens

SUBMITTER: Ray Dunn

PROVIDER: E-MTAB-5959 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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