Transcription profiling of heart left ventricle from patients with idopathic dilated cardiomyopathy and normal controls

ABSTRACT: The mechanisms underlying the balancing of circulatory demands against changes in cellular homeostasis and cell death/survival signaling in heart muscle disease are still not fully understood. We employed the ABI high-density oligonucleotide microarrays containing 31,700 sixty-mer oligonucleotide probes (representing 27,868 individual human genes) to determine differential gene expression in idiopathic dilated cardiomyopathy (DCM) (n=5) compared to normal controls (n=4), in order to systematically characterize disease-induced alterations in gene expression that may provide a basis for deciphering such mechanisms.

ORGANISM(S): Homo sapiens

DISEASE(S): idiopathic dilated cardiomyopathy

SUBMITTER: Dilek Colak 

PROVIDER: E-TABM-480 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress