Genotyping of human Infant ALL samples to detect MLL-cooperating aberrations

ABSTRACT: In this study we explored the genotype of Infant ALL to detect MLL-cooperating aberrations, hidden to conventional techniques. In order to limit further heterogeneity, we focused on patients carrying the t(4;11) translocation, the most frequent genetic abnormality in Infant ALL. Final aim was to get new insights into the leukemia pathogenesis of this rare and aggressive disease, as well as providing the basis for discovering new genes for targeted therapy.

ORGANISM(S): Homo sapiens

SUBMITTER: Michela Bardini 

PROVIDER: E-TABM-511 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress