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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of six pairs of affected and non-affected male F2 mice selected on the basis of their motor activity levels

ABSTRACT: Mice were obtained from in house breeding of C57BL/6J and C57BL/6J-Chr 1A/Na breeding pairs (Jackson Laboratories, USA). To produce F1 hybrids, C57BL/6J females were mated with C57BL/6J-Chr 1A/Na males. The F1 hybrids were intercrossed, producing 82 F2 progeny (41 males and 41 females). Microarray analysis was performed on six pairs of affected and non-affected male animals from the F2 progeny selected on the basis of their motor activity levels (average daily levels of distance moved over a 3 days recording: 768±74 cm/hr (affected) versus 1765±175 cm/hr (non-affected)(p<0.0001).

ORGANISM(S): Mus musculus

SUBMITTER: Hein van Lith

PROVIDER: E-UMCU-22 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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