Biphasic oxygen tension promotes the formation of transferable blastocysts in patients without euploid embryos in previous monophasic oxygen cycles.

ABSTRACT: This study evaluated whether the concentration of biphasic O₂ (5-2%) promotes the formation of qualified blastocysts (QBs) and euploid blastocysts and the probability of cycles with transferable blastocysts. The paired experimental design included a total 90 patients (180 cycles) without euploid blastocysts in previous monophasic O₂ (5%) cycles were enrolled for an additional cycle of biphasic O₂ (5-2%). In the biphasic O₂ (5-2%) group, the QB rate (35.8%, 225/628) was significantly higher than that in the monophasic O₂ (5%) group (23.5%, 137/582; p < 0.001). In addition, the euploid blastocyst number (0.5 ± 0.8) and the percentage of cycles with transferable blastocysts were significantly higher in the biphasic O₂ (5-2%) gr

SUBMITTER: Chen HH 

PROVIDER: S-EPMC10017668 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature