Cerebral oxygenation and autoregulation during rewarming on cardiopulmonary bypass.

ABSTRACT:

Background

Rewarming on cardiopulmonary bypass (CPB) is associated with increased metabolic demands; however, it remains unclear whether cerebral autoregulation is affected during this phase. This RCT aims to describe the effects of 20% supranormal, compared to normal CPB flow, on monitoring signs of inadequate perfusion, oxygenation, and disturbed cerebral autoregulation, during the rewarming phase of CPB.

Method

Thirty two patients scheduled for coronary artery bypass grafting were allocated to a Control group (n = 16) receiving a CPB pump flow corresponding to preoperatively measured cardiac output, and an Intervention group (n = 16) receiving the corresponding CPB pump flow increased by 20% during rewarming. Cerebral Oximetry Index (COx) was calculated with

SUBMITTER: Arthursson H 

PROVIDER: S-EPMC10026164 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature