At-home urine estrone-3-glucuronide quantification predicts oocyte retrieval outcomes comparably with serum estradiol.

ABSTRACT:

Objective

To investigate the feasibility of monitoring urine estrone-3-glucuronide (E3G) with an at-home device during gonadotropin stimulation for in vitro fertilization and oocyte cryopreservation.

Design

Prospective, observational cohort study.

Setting

Private fertility clinic.

Patients

Thirty patients undergoing stimulation with a gonadotropin-releasing hormone antagonist protocol for in vitro fertilization or oocyte cryopreservation.

Interventions

Daily collection of the first urine in the morning during stimulation and analysis performed at home by each patient with the Mira Fertility Tracker.

Main outcome measures

Primary outcomes were correlation of urine E3G and serum estradiol (E2) concentrations on the day of trigger to the number of to

SUBMITTER: Nakhuda GS 

PROVIDER: S-EPMC10028475 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature