The association of center volume with transplant outcomes in selected high-risk groups in kidney transplantation.

ABSTRACT:

Background

In context of increasing complexity and risk of deceased kidney donors and transplant recipients, the impact of center volume (CV) on the outcomes of high-risk kidney transplants(KT) has not been well determined.

Methods

We examined the association of CV and outcomes among 285 U.S. transplant centers from 2000-2016. High-risk KT were defined as recipient age ≥ 70 years, body mass index (BMI) ≥ 35 kg/m², receiving kidneys from donors with kidney donor profile index(KDPI) ≥ 85%, acute kidney injury(AKI), hepatitisC + . Average annual CV for the specific-high-risk KT categorized in tertiles. Death-Censored-Graft-Loss(DCGL) and death at 3 months, 1, 5, and 10 years were compared between CV tertiles using Cox-regression models.

Results

Two hundred fif

SUBMITTER: Merzkani M 

PROVIDER: S-EPMC10029277 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature