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Interaction effect between fasting plasma glucose and lipid profiles on mortality of peritoneal dialysis patients.


ABSTRACT:

Background

Peritoneal dialysis (PD) patients have a high risk of abnormal glucose and lipids metabolism.

Objective

We investigated the effects of baseline fasting plasma glucose (FPG) as well as its interaction with lipid profiles on all-cause and cardiovascular disease (CVD) cause-specific mortality in PD patients.

Methods

A total of 1995 PD patients were enrolled. Kaplan-Meier survival curves and Cox regression models were performed to assess the association of FPG levels with mortality in PD patients.

Results

During a median (25th-75th quartile) follow-up period of 48.1 (21.8-77.9) months, 567 (28.4%) patients died, including 282 (14.1%) CVD deaths. Kaplan-Meier survival curves showed that all-cause and CVD cause-specific mortality increased significantly wi

SUBMITTER: Xu Y 

PROVIDER: S-EPMC10061421 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature