Intravesical aminoglycoside instillations as prophylaxis for recurrent urinary tract infection: patient satisfaction, long-term safety and efficacy.

ABSTRACT:

Background

Recurrent urinary tract infections (UTIs) are common, especially in women. When oral antimicrobial prophylaxis is ineffective or not possible due to allergies or antimicrobial resistance, intravesical aminoglycoside instillations (IAIs) are a non-systemic alternative.

Objectives

To assess treatment satisfaction, long-term safety and efficacy of IAIs for recurrent UTI.

Methods

We conducted a cohort study using data collected between January 2013 and June 2022 at the Leiden University Medical Center. Adult patients with recurrent UTI who received prophylactic IAI were eligible for inclusion. Treatment satisfaction was assessed through a survey. Data on serum aminoglycoside concentrations, cystoscopy results and number of recurrences were obtained through char

SUBMITTER: Bilsen MP 

PROVIDER: S-EPMC10077025 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature