Cross-modal modulation gates nociceptive inputs in Drosophila.

ABSTRACT: Animals' response to a stimulus in one sensory modality is usually influenced by other modalities.¹ One important type of multisensory integration is the cross-modal modulation, in which one sensory modality modulates (typically inhibits) another. Identification of the mechanisms underlying cross-modal modulations is crucial for understanding how sensory inputs shape animals' perception and for understanding sensory processing disorders.^2,3,4 However, the synaptic and circuit mechanisms that underlie cross-modal modulation are poorly understood. This is due to the difficulty of separating cross-modal modulation from multisensory integrations in neurons that receive excitatory inputs from two or more sensory modalities^5<

SUBMITTER: Pan G 

PROVIDER: S-EPMC10089977 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature