Risk of progression from pre-diabetes to type 2 diabetes in a large UK adult cohort.

ABSTRACT:

Aims

People with pre-diabetes are at high risk of progressing to type 2 diabetes. This progression is not well characterised by ethnicity, deprivation and age, which we describe in a large cohort of individuals with pre-diabetes.

Methods

A retrospective cohort study with The Health Improvement Network (THIN) database was conducted. Patients aged 18 years and over and diagnosed with pre-diabetes [HbA1c 42 mmol/mol (6.0%) to 48 mmol/mol (6.5%) were included]. Cox proportional hazards regression was used to calculate adjusted hazard rate ratios (aHR) for the risk of progression from pre-diabetes to type 2 diabetes for each of the exposure categories [ethnicity, deprivation (Townsend), age and body mass index (BMI)] separately.

Results

Of the baseline population with pre-

SUBMITTER: Gardner MP 

PROVIDER: S-EPMC10099224 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature