Biomarkers associated with the development of comorbidities in patients with atopic dermatitis: A systematic review.

ABSTRACT: Biomarkers associated with the development of comorbidities in atopic dermatitis (AD) patients have been reported, but have not yet been systematically reviewed. Seven electronic databases were searched, from database inception to September 2021. English language randomized controlled trials, prospective and retrospective cohort, and case-control studies that investigated the association between a biomarker and the development of comorbidities in AD patients were included. Two authors independently screened the records for eligibility, one extracted all data, and critically appraised the quality of studies and risk of bias. Fifty six articles met the inclusion criteria, evaluating 146 candidate biomarkers. The most frequently reported biomarkers were filaggrin mutations and allergen specif

SUBMITTER: Broderick C 

PROVIDER: S-EPMC10107168 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature