Eight-hour time-restricted eating does not lower daily myofibrillar protein synthesis rates: A randomized control trial.

ABSTRACT:

Objective

This study aimed to assess the impact of time-restricted eating (TRE) on integrated skeletal muscle myofibrillar protein synthesis (MyoPS) rates in males with overweight/obesity.

Methods

A total of 18 healthy males (age 46 ±  5 years; BMI: 30 ± 2 kg/m² ) completed this exploratory, parallel, randomized dietary intervention after a 3-day lead-in diet. Participants then consumed an isoenergetic diet (protein: ~1.0 g/kg body mass per day) following either TRE (10:00 a.m. to 6:00 p.m.) or an extended eating control (CON; 8:00 a.m. to 8:00 p.m.) protocol for 10 days. Integrated MyoPS rates were measured using deuterated water administration with repeated saliva, blood, and muscle sampling. Secondary measures included continuous glucose monitoring and body com

SUBMITTER: Parr EB 

PROVIDER: S-EPMC10107304 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature