The impact of C-reactive protein-albumin-lymphocyte (CALLY) index on the prognosis of patients with distal cholangiocarcinoma following pancreaticoduodenectomy.

ABSTRACT:

Aim

The C-reactive protein (CRP)-albumin-lymphocyte (CALLY) index is a novel inflammation-based biomarker, which has been associated with long-term outcomes in patients with hepatocellular carcinoma. We aimed to investigate whether the CALLY index can predict the prognosis for distal cholangiocarcinoma after pancreaticoduodenectomy.

Methods

The study comprised 143 patients who had undergone primary pancreaticoduodenectomy for distal cholangiocarcinoma between 2002 to 2019. The CALLY index was defined as (albumin × lymphocyte)/ (CRP × 10⁴). We investigated the association of CALLY index with disease-free survival and overall survival by univariate and multivariate analyses.

Results

Eighty-seven (61%) patients had a preoperative CALLY index <3.5. In multivari

SUBMITTER: Tsunematsu M 

PROVIDER: S-EPMC10154875 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature