COVID-19 vaccine effectiveness among healthcare workers: a hospital-based cohort study.

ABSTRACT:

Objectives

Healthcare workers (HCWs) were the first to be prioritised for COVID-19 vaccination. This study aims to estimate the COVID-19 vaccine effectiveness (VE) against SARS-CoV-2 symptomatic infection among HCWs in Portuguese hospitals.

Design

Prospective cohort study.

Setting and participants

We analysed data from HCWs (all professional categories) from three central hospitals: one in the Lisbon and Tagus Valley region and two in the central region of mainland Portugal, between December 2020 and March 2022. VE against symptomatic SARS-CoV-2 infection was estimated as one minus the confounder adjusted HRs by Cox models considering age group, sex, self-reported chronic disease and occupational exposure to patients diagnosed with COVID-19 as adjustment variables.

SUBMITTER: Gaio V 

PROVIDER: S-EPMC10163328 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature