Improved gestational diabetes screening protocol.

ABSTRACT:

Objectives

This work aimed to assess the diagnostic validity of two approaches for the screening of gestational diabetes mellitus (GDM) with less discomfort for pregnant women.

Methods

A prospective diagnostic validation study was conducted with 2007 pregnant women. According to risk factors for GDM, women were classified into high-risk and low-risk groups. The current diagnostic procedure, based on oral glucose overload, was followed; simultaneously HbA_1c was tested and an algorithm combining both biomarkers was applied.

Results

In the low-risk group, the Glucose challenge test (GCT) showed a higher area under the curve (AUC 0.953; 95% CI 0.915-0.992) than the HbA_1c test (0.688; 95% CI 0.541-0.834). The best GCT cut-off, 153.5 mg/dL (8.52 mmol/L

SUBMITTER: Calero Rojas M 

PROVIDER: S-EPMC10197282 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature