Quantitative Sleep Electroencephalogram in Parkinson's Disease: A Case-Control Study.

ABSTRACT:

Background

Sleep disorders are common in Parkinson's disease (PD) and include alterations in sleep-related EEG oscillations.

Objective

This case-control study tested the hypothesis that patients with PD would have a lower density of Scalp-Slow Wave (SW) oscillations and higher slow-to-fast frequencies ratio in rapid eye movement (REM) sleep than non-PD controls. Other sleep-related quantitative EEG (qEEG) features were also examined, including SW morphology, sleep spindles, and Scalp-SW spindle phase-amplitude coupling.

Methods

Polysomnography (PSG)-derived sleep EEG was compared between PD participants (n = 56) and non-PD controls (n = 30). Following artifact rejection, sleep qEEG analysis was performed in frontal and central leads. Measures included SW density and m

SUBMITTER: Memon AA 

PROVIDER: S-EPMC10200139 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature