A systematic review of the protein composition of whole saliva in subjects with healthy periodontium compared with chronic periodontitis.

ABSTRACT:

Context

Periodontitis is a chronic multifactorial inflammatory disease linked to oral microbiota dysbiosis. This disease progresses to infection that stimulates a host immune/inflammatory response, with progressive destruction of the tooth-supporting structures.

Objective

This systematic review aims to present a robust critical evaluation of the evidence of salivary protein profiles for identifying oral diseases using proteomic approaches and summarize the use of these approaches to diagnose chronic periodontitis.

Data sources

A systematic literature search was conducted from January 1st, 2010, to December 1st, 2022, based on PICO criteria following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and by searching the three da

SUBMITTER: Sanchez-Medrano AG 

PROVIDER: S-EPMC10208468 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature