Bacterial diet affects the age-dependent decline of associative learning in Caenorhabditis elegans.
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ABSTRACT:
SUBMITTER: Higurashi S
PROVIDER: S-EPMC10229132 | biostudies-literature | 2023 May
REPOSITORIES: biostudies-literature
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Bacterial diet affects the age-dependent decline of associative learning in <i>Caenorhabditis elegans</i>.
Higurashi Satoshi S Tsukada Sachio S Aleogho Binta Maria BM Park Joo Hyun JH Al-Hebri Yana Y Tanaka Masaru M Nakano Shunji S Mori Ikue I Noma Kentaro K
eLife 20230530
The causality and mechanism of dietary effects on brain aging are still unclear due to the long time scales of aging. The nematode <i>Caenorhabditis elegans</i> has contributed to aging research because of its short lifespan and easy genetic manipulation. When fed the standard laboratory diet, <i>Escherichia coli</i>, <i>C. elegans</i> experiences an age-dependent decline in temperature-food associative learning, called thermotaxis. To address if diet affects this decline, we screened 35 lactic ...[more]
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