Differences in cortical morphology and child internalizing or externalizing problems: Accounting for the co-occurrence.

ABSTRACT:

Background

Childhood internalizing and externalizing problems frequently co-occur. Many studies report neural correlates of either internalizing or externalizing problems, but few account for their co-occurrence. We aimed to assess specific cortical substrates of these psychiatric problems.

Methods

We used data from 9635 children aged 9-11 years in the baseline Adolescent Brain Cognitive Development Study. Internalizing and externalizing problem composite scales scores were derived from the Child Behavior Checklist. We standardized FreeSurfer-derived volumes of 68 cortical regions. We examined internalizing and externalizing problems separately and jointly (covariate-adjustment) in relation to cortical volumes, with and without adjusting for total brain volume (TBV) in multi

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC10242825 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature