Maternal risk of hypertension 7-15 years after pregnancy: clues from the placenta.

ABSTRACT:

Objective

To assess whether pre-eclampsia (PE)-related placental/extraplacental membrane findings are linked to moderately elevated blood pressure (BP) in pregnancy and later-life hypertension.

Design

Prospective cohort.

Setting

52 prenatal clinics, 5 Michigan communities.

Sample

The POUCH Study recruited women at 16-27 weeks' gestation (1998-2004) and studied a sub-cohort in depth. This sample (n = 490) includes sub-cohort women with detailed placental assessments and cardiovascular health evaluations 7-15 years later in the POUCHmoms follow-up study.

Methods

PE-related placental/extraplacental membrane findings (i.e. mural hyperplasia, unaltered/abnormal vessels or atherosis in decidua; infarcts) were evaluated in relation to pregnancy BP and odds of S

SUBMITTER: Holzman CB 

PROVIDER: S-EPMC10243612 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature