Pretherapy ¹⁸F-FDG PET/CT in Predicting Disease Relapse in Patients With Immunoglobulin G4-Related Disease: A Prospective Study.

ABSTRACT:

Objective

To investigate whether the levels of inflammation detected by ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) can predict disease relapse in immunoglobulin G4-related disease (IgG4-RD) patients receiving standard induction steroid therapy.

Materials and methods

This prospective study analyzed pretherapy FDG PET/CT images from 48 patients (mean age, 63 ± 12.9 years; 45 males and 3 females) diagnosed with IgG4-RD between September 2008 and February 2018, who subsequently received standard induction steroid therapy as the first-line treatment. Multivariable Cox proportional hazards models were used to identify the potential prognostic factors associated with relapse-free survival (RFS).

Results

The median foll

SUBMITTER: Cheng MF 

PROVIDER: S-EPMC10248362 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature