An odorant binding protein is involved in counteracting detection-avoidance and Toll-pathway innate immunity.

ABSTRACT:

Introduction

Odorant-binding proteins (OBPs) are a class of small molecular weight soluble proteins that exist as expanded gene families in all insects, acting as ligand carriers mediating olfaction and other physiological processes. During fungal infection, a subset of insect OBPs were shown to be differentially expressed.

Objectives

We tested whether the altered expression of insect OBPs during pathogenic infection plays a role in behavioral or immune interactions between insect hosts and their pathogens.

Methods

A wide range of techniques including RNAi-directed knockdown, heterologous protein expression, electrophysiological/behavioral analyses, transcriptomics, gut microbiome analyses, coupled with tandem mass spectrometry ion monitoring, were used to characteriz

SUBMITTER: Zhang W 

PROVIDER: S-EPMC10248801 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature