Dataset Information

25-Hydroxyvitamin D supplementation and health-service utilization for upper respiratory tract infection in young children.

ABSTRACT:

Objective

Upper respiratory tract infections (URTI) are the most common and costly condition of childhood. Low vitamin D levels have been hypothesized as a risk factor for URTI. The primary objective was to determine if serum vitamin D levels were associated with health-service utilization (HSU) for URTI including hospital admission, emergency department visits and outpatient sick visits. The secondary objectives were to determine whether oral vitamin D supplementation in pregnancy or childhood was associated with HSU for URTI.

Design

Cohort study. HSU was determined by linking each child's provincial health insurance number to health administrative databases. Multivariable quasi Poisson regression was used to evaluate the association between 25-hydroxyvitamin D, vitamin D supplementation and HSU for URTI.

Setting

Toronto, Canada.

Subjects

Children participating in the TARGet Kids! network between 2008 and 2013.

Results

Healthy children aged 0-5 years (n 4962) were included; 52 % were male and mean 25-hydroxyvitamin D was 84 nmol/l (range 11-355 nmol/l). There were 105 (2 %), 721 (15 %) and 3218 (65 %) children with at least one hospital admission, emergency department visit or outpatient sick visit for URTI, respectively. There were no statistically significant associations between 25-hydroxyvitamin D or vitamin D supplementation and HSU for URTI.

Conclusions

A clinically meaningful association between vitamin D (continuously and dichotomized at <50 and <75 nmol/l) and HSU for URTI was not identified. While vitamin D may have other benefits for health, reducing HSU for URTI does not appear to be one of them.

SUBMITTER: Omand JA

PROVIDER: S-EPMC10261635 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature

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Publications

25-Hydroxyvitamin D supplementation and health-service utilization for upper respiratory tract infection in young children.

Omand Jessica A JA To Teresa T O'Connor Deborah L DL Parkin Patricia C PC Birken Catherine S CS Thorpe Kevin E KE Maguire Jonathon L JL

Public health nutrition 20170605 10

<h4>Objective</h4>Upper respiratory tract infections (URTI) are the most common and costly condition of childhood. Low vitamin D levels have been hypothesized as a risk factor for URTI. The primary objective was to determine if serum vitamin D levels were associated with health-service utilization (HSU) for URTI including hospital admission, emergency department visits and outpatient sick visits. The secondary objectives were to determine whether oral vitamin D supplementation in pregnancy or ch ...[more]

PMID: 28578751

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Dataset Information

25-Hydroxyvitamin D supplementation and health-service utilization for upper respiratory tract infection in young children.

Objective

Design

Setting

Subjects

Results

Conclusions

Publications

25-Hydroxyvitamin D supplementation and health-service utilization for upper respiratory tract infection in young children.

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