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Molecular Imaging for Estrogen Receptor-Positive Breast Cancer: Clinical Applications of Whole Body and Dedicated Breast Positron Emission Tomography.


ABSTRACT: 18F-fluoroestradiol (18F-FES) is a Food and Drug Administration-approved radiopharmaceutical used for molecular imaging of the estrogen receptor (ER). When combined with PET, 18F-FES may improve the diagnosis of ER-positive breast cancer in the metastatic setting and provide insights into tumor heterogeneity. In this article, we review data on the use of 18F-FES imaging for treatment selection, staging, imaging lobular breast cancer, and the novel breast specific imaging tool, dedicated breast PET.

SUBMITTER: Goodman K 

PROVIDER: S-EPMC10277169 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

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Molecular Imaging for Estrogen Receptor-Positive Breast Cancer: Clinical Applications of Whole Body and Dedicated Breast Positron Emission Tomography.

Goodman Kent K   Abel Mary Kathryn MK   Lawhn-Heath Courtney C   Molina-Vega Julissa J   Jones Ella F EF   Mukhtar Rita A RA  

Surgical oncology clinics of North America 20221001 4


<sup>18</sup>F-fluoroestradiol (<sup>18</sup>F-FES) is a Food and Drug Administration-approved radiopharmaceutical used for molecular imaging of the estrogen receptor (ER). When combined with PET, <sup>18</sup>F-FES may improve the diagnosis of ER-positive breast cancer in the metastatic setting and provide insights into tumor heterogeneity. In this article, we review data on the use of <sup>18</sup>F-FES imaging for treatment selection, staging, imaging lobular breast cancer, and the novel brea  ...[more]

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