Unknown

Dataset Information

0

Characterizing the relationship between coronavirus disease 2019 (COVID-19) and central-line-associated bloodstream infection (CLABSI) and assessing the impact of a nursing-focused CLABSI reduction intervention during the COVID-19 pandemic.


ABSTRACT:

Objective

To examine the impact of SARS-CoV-2 infection on CLABSI rate and characterize the patients who developed a CLABSI. We also examined the impact of a CLABSI-reduction quality-improvement project in patients with and without COVID-19.

Design

Retrospective cohort analysis.

Setting

Academic 889-bed tertiary-care teaching hospital in urban Los Angeles.

Patients or participants

Inpatients 18 years and older with CLABSI as defined by the National Healthcare Safety Network (NHSN).

Intervention(s)

CLABSI rate and patient characteristics were analyzed for 2 cohorts during the pandemic era (March 2020-August 2021): COVID-19 CLABSI patients and non-COVID-19 CLABSI patients, based on diagnosis of COVID-19 during admission. Secondary analyses were non-COVID-19 CLABSI rate versus a historical control period (2019), ICU CLABSI rate in COVID-19 versus non-COVID-19 patients, and CLABSI rates before and after a quality- improvement initiative.

Results

The rate of COVID-19 CLABSI was significantly higher than non-COVID-19 CLABSI. We did not detect a difference between the non-COVID-19 CLABSI rate and the historical control. COVID-19 CLABSIs occurred predominantly in the ICU, and the ICU COVID-19 CLABSI rate was significantly higher than the ICU non-COVID-19 CLABSI rate. A hospital-wide quality-improvement initiative reduced the rate of non-COVID-19 CLABSI but not COVID-19 CLABSI.

Conclusions

Patients hospitalized for COVID-19 have a significantly higher CLABSI rate, particularly in the ICU setting. Reasons for this increase are likely multifactorial, including both patient-specific and process-related issues. Focused quality-improvement efforts were effective in reducing CLABSI rates in non-COVID-19 patients but were less effective in COVID-19 patients.

SUBMITTER: Ben-Aderet MA 

PROVIDER: S-EPMC10369209 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature

altmetric image

Publications

Characterizing the relationship between coronavirus disease 2019 (COVID-19) and central-line-associated bloodstream infection (CLABSI) and assessing the impact of a nursing-focused CLABSI reduction intervention during the COVID-19 pandemic.

Ben-Aderet Michael A MA   Madhusudhan Meghan S MS   Haroun Pishoy P   Almario Matthew J P MJP   Raypon Ryan R   Fawcett Sharon S   Johnson Julie J   Girard Anita A   Griner Todd T   Sheffield Lorraine L   Grein Jonathan D JD  

Infection control and hospital epidemiology 20220831 7


<h4>Objective</h4>To examine the impact of SARS-CoV-2 infection on CLABSI rate and characterize the patients who developed a CLABSI. We also examined the impact of a CLABSI-reduction quality-improvement project in patients with and without COVID-19.<h4>Design</h4>Retrospective cohort analysis.<h4>Setting</h4>Academic 889-bed tertiary-care teaching hospital in urban Los Angeles.<h4>Patients or participants</h4>Inpatients 18 years and older with CLABSI as defined by the National Healthcare Safety  ...[more]

Similar Datasets

2022-04-08 | GSE178246 | GEO
| S-EPMC10015264 | biostudies-literature
| S-EPMC7405836 | biostudies-literature
| S-EPMC9551181 | biostudies-literature
| S-EPMC10229040 | biostudies-literature
2022-04-08 | GSE178331 | GEO
| S-EPMC7167217 | biostudies-literature
| S-EPMC7429403 | biostudies-literature
| 2346925 | ecrin-mdr-crc