Impact of para aortic lymph node removal on survival following resection for pancreatic adenocarcinoma.

ABSTRACT:

Introduction

For PDAC patients undergoing resection, it remains unclear whether metastases to the paraaortic lymph nodes (PALN+) have any prognostic significance and whether metastases should lead to the operation not being carried out. Our hypothesis is that PALN + status would be associated with short overall survival (OS) compared with PALN-, but longer OS compared with patients undergoing surgical exploration only (EXP).

Methods

Patients with registered PALN removal from the nationwide Danish Pancreatic Cancer Database (DPCD) from May 1st 2011 to December 31st 2020 were assessed. A cohort of PDAC patients who only had explorative laparotomy due to non-resectable tumors were also included (EXP group). Survival analysis between groups were performed with cox-regression in

SUBMITTER: Sillesen M 

PROVIDER: S-EPMC10394933 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature