Offspring-sex modifies the association between early-pregnancy adiposity and 2-year-old total physical activity - The Glowing Study.

ABSTRACT:

Background

Rodent models suggest that in utero exposure to under and overnutrition programs offspring physical activity (PA) behaviors. Such nexus has not been established in humans. This study evaluated the association of early pregnancy maternal adiposity with offspring PA at age 2 years (2-yo-PA) taking into consideration prenatal and postnatal factors.

Methods

Women (n=153) were enrolled early in pregnancy (<10 weeks). At enrollment, maternal adiposity [air displacement plethysmography, fat mass index (FMI, kg/m²)] and PA (accelerometers, activity counts) were measured, and age, race, and education self-reported. Gestational weight gain was measured at the research facility. Offspring birthweight and sex were self-reported. At age 2 years, parental feed

SUBMITTER: Diaz E 

PROVIDER: S-EPMC10402255 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature