Long-term health-related quality of life in patients with advanced esophagogastric cancer receiving first-line systemic therapy.

ABSTRACT:

Purpose

To investigate the effect of systemic therapy on health-related quality of life (HRQoL) in patients with advanced esophagogastric cancer in daily clinical practice. This study assessed the HRQoL of patients with esophagogastric cancer during first-line systemic therapy, at disease progression, and after progression in a real-world context.

Methods

Patients with advanced esophagogastric cancer (2014-2021) receiving first-line systemic therapy registered in the Prospective Observational Cohort Study of Oesophageal-gastric cancer (POCOP) were included (n = 335). HRQoL was measured with the EORTC QLQ-C30 and QLQ-OG25. Outcomes of mixed-effects models were presented as adjusted mean changes.

Results

Results of the mixed-effect models showed the largest significant

SUBMITTER: Pape M 

PROVIDER: S-EPMC10425291 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature