Health-related quality of life in patients receiving long-term opioid therapy: a systematic review with meta-analysis.

ABSTRACT:

Purpose

Over 25 million Americans reported having daily pain and between 5 and 8 million Americans used opioids to treat chronic pain in 2012. This is the first systematic review with meta-analysis to determine the effects of long-term opioid use on the Physical Component Summary (PCS) score and Mental Component Summary (MCS) scores of a Health-Related Quality of Life instrument in adults without opioid use disorder.

Methods

The a priori eligibility criteria for the PubMed (MEDLINE), Scopus, and PsyINFO searches were (1) randomized controlled trial, (2) at least one opioid intervention group, (3) minimum of 4-week duration of opioid use, (4) comparative control group, and (5) adults ≥18 years that do not have dominant disease. The unit of analysis was the standardized mean d

SUBMITTER: Thornton JD 

PROVIDER: S-EPMC5511070 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature