Exaggerated blood pressure response to standing in young-to-middle-age subjects: prevalence and factors involved.

ABSTRACT:

Purpose

To investigate the prevalence of orthostatic hypertension and the association of the blood pressure (BP) level, supine BP decline, and white-coat effect with the orthostatic pressor response.

Methods

We studied 1275 young-to-middle-age individuals with stage-1 hypertension. Orthostatic response was assessed three times over a 3 month period. The white-coat effect was assessed at baseline and after 3 months, and was calculated as the difference between office and average 24 h BP. In 660 participants, urinary epinephrine and norepinephrine were also measured.

Results

An orthostatic systolic BP increase ≥ 20 mmHg was observed in 0.6-1.2% of the subjects during the three visits. Using the 20 mmHg cut-off, the prevalence of orthostatic hypertension was 0.6%. An ort

SUBMITTER: Palatini P 

PROVIDER: S-EPMC10439022 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature