Factors Influencing Properties of Spider Silk Coatings and Their Interactions within a Biological Environment.

ABSTRACT: Biomaterials are an indispensable part of biomedical research. However, although many materials display suitable application-specific properties, they provide only poor biocompatibility when implanted into a human/animal body leading to inflammation and rejection reactions. Coatings made of spider silk proteins are promising alternatives for various applications since they are biocompatible, non-toxic and anti-inflammatory. Nevertheless, the biological response toward a spider silk coating cannot be generalized. The properties of spider silk coatings are influenced by many factors, including silk source, solvent, the substrate to be coated, pre- and post-treatments and the processing technique. All these factors consequently affect the biological response of the environment and the putativ

SUBMITTER: Trossmann VT 

PROVIDER: S-EPMC10455157 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature