The variation of insulin like growth factor 2 maker is associated with growth traits in Thai native (Kradon) pigs.

ABSTRACT:

Objective

This study was conducted to investigate polymorphisms of the melanocortin-4 receptor (MC4R) and insulin like growth factor 2 (IGF2) genes and to evaluate the growth traits affected by such polymorphisms in Thai native (Kradon) pigs.

Methods

Blood samples and productive data from 91 Kradon pigs were collected. DNA was extracted and quantified, the IGF2 and MC4R genes were amplified, and the polymerase chain reaction (PCR) produces were digested using the PCR-restriction fragment length polymorphism (PCR-RFLP) technique. Genotyping was performed, and the association between genotypes and growth traits on the birth and weaning weights were evaluated.

Results

The IGF2 intron7 g.162G>C variations in Kradon pigs were found in three genotypes: i) GG, ii) GC, and ii

SUBMITTER: Ampaporn K 

PROVIDER: S-EPMC10472148 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature