Indexed oxygen delivery during pediatric cardiopulmonary bypass is a modifiable risk factor for postoperative acute kidney injury.

ABSTRACT:

Background

Acute kidney injury after pediatric cardiac surgery is a common complication with few established modifiable risk factors. We sought to characterize whether indexed oxygen delivery during cardiopulmonary bypass was associated with postoperative acute kidney injury in a large pediatric cohort.

Methods

This was a retrospective analysis of patients under 1 year old undergoing cardiac surgery with cardiopulmonary bypass between January 1, 2013, and January 1, 2020. Receiver operating characteristic curves across values ranging from 260 to 400 mL/min/m² were used to identify the indexed oxygen delivery most significantly associated with acute kidney injury risk.

Results

We included 980 patients with acute kidney injury occurring in 212 (21.2%). After

SUBMITTER: Dreher M 

PROVIDER: S-EPMC10487348 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature