Bidirectional association between infectious gastroenteritis and inflammatory bowel disease: a population-based study.

ABSTRACT:

Background

Intertwined association between infectious gastroenteritis (IGE) and inflammatory bowel disease (IBD) has not been investigated clearly. We aimed to examine the bidirectional association between IGE and IBD.

Methods

A bidirectional study using the Taiwan National Health Insurance Research Database was designed. Through a case-control design, we identified 2899 new IBD cases during 2006-2017 and matched to 28,990 non-IBD controls. We used conditional logistic regression model to estimate odds ratios (OR) of IBD for previous IGE in different exposure time-windows within 5-years before IBD diagnosis and Poisson regression model to estimate incidence rate ratio (IRR) of subsequent IGE for IBD group to non-IBD group.

Results

The mean age at the initial IBD diagn

SUBMITTER: Tu KC 

PROVIDER: S-EPMC10494362 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature