The association between persistent cognitive difficulties and depression and functional outcomes in people with major depressive disorder.

ABSTRACT:

Background

Cognitive symptoms are common during and following episodes of depression. Little is known about the persistence of self-reported and performance-based cognition with depression and functional outcomes.

Methods

This is a secondary analysis of a prospective naturalistic observational clinical cohort study of individuals with recurrent major depressive disorder (MDD; N = 623). Participants completed app-based self-reported and performance-based cognitive function assessments alongside validated measures of depression, functional disability, and self-esteem every 3 months. Participants were followed-up for a maximum of 2-years. Multilevel hierarchically nested modelling was employed to explore between- and within-participant variation over time to identify whe

SUBMITTER: Matcham F 

PROVIDER: S-EPMC10520589 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature