The association between plasma osmolality and in-hospital mortality in the first 24 h after neonatal intensive care unit admission.

ABSTRACT:

Background

Perturbation of osmolality is associated with increased mortality in adults and children in critically ill conditions. However, it is still unclear whether osmolality imbalance impacts the prognosis of critically ill infants. This study aimed to investigate the relationship between plasma osmolality and prognosis in critically ill infants within 24 h of admission.

Methods

This retrospective study enrolled 1,042 infants who had plasma osmolality data from 2010 to 2018. The initial plasma osmolality (within 24 h after admission) was extracted from the pediatric intensive care database (PIC V1.1). The locally weighted scatter-plot smoothing (LOWESS) and restricted cubic splines (RCS) methods were used to explore the approximate relationship between plasma osmolality

SUBMITTER: Liu W 

PROVIDER: S-EPMC10522910 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature