Efficient Simultaneous Detection of Metabolites Based on Electroenzymatic Assembly Strategy.

ABSTRACT: Objective and Impact Statement: We describe an electroenzymatic mediator (EM) sensor based on an electroenzymatic assembly peak separation strategy, which can efficiently realize the simultaneous detection of 3 typical cardiovascular disease (CVD) metabolites in 5 μl of plasma under one test. This work has substantial implications toward improving the efficiency of chronic CVD assessment. Introduction: Monitoring CVD of metabolites is strongly associated with disease risk. Independent and time-consuming detection in hospitals is unfavorable for chronic CVD management. Methods: The EM was flexibly designed by the cross-linking of electron mediators and enzymes, and 3 EM layers with different characteristics were assembled on one electrode. Electrons were transferred und

SUBMITTER: Zheng A 

PROVIDER: S-EPMC10530654 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature