Adverse childhood experiences in early life increase the odds of depression among adults with multiple sclerosis.

ABSTRACT:

Background

Adverse childhood experiences are demonstrated risk factors for depression, a common co-morbidity of multiple sclerosis, but are understudied among people with multiple sclerosis.

Objective

Estimate the association between adverse childhood experiences and depression among 1,990 adults with multiple sclerosis.

Methods

Participants were members of Kaiser Permanente Northern California from two studies between 2006 and 2021 and were diagnosed with multiple sclerosis by a neurologist. Adverse childhood experiences were assessed using two instruments, including the Behavioral Risk Factor Surveillance System. Participants self-reported ever experiencing a major depressive episode. Meta-analysis random effects models and logistic regression were used to estimate

SUBMITTER: Guerrero KS 

PROVIDER: S-EPMC10552460 | biostudies-literature | 2023 Oct-Dec

REPOSITORIES: biostudies-literature