Quantitative ultrasonographic examination of cerebral white matter by pixel brightness intensity as marker of middle-term neurodevelopment: a prospective observational study.

ABSTRACT: Non-cystic white matter (WM) injury has become prevalent among preterm newborns and is associated with long-term neurodevelopmental impairment. Magnetic resonance is the gold-standard for diagnosis; however, cranial ultrasound (CUS) is more easily available but limited by subjective interpretation of images. To overcome this problem, we enrolled in a prospective observational study, patients with gestational age at birth < 32 weeks with normal CUS scans or grade 1 WM injury. Patients underwent CUS examinations at 0-7 days of life (T₀), 14-35 days of life (T₁), 37^0/7-41^6/7 weeks' postmenstrual age (T₂), and 42^0/7-52^0/7 weeks' postmenstrual age (T₃). The echogenicity of parieto-occipital periventricular W

SUBMITTER: Laccetta G 

PROVIDER: S-EPMC10556025 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature