Acute myocardial infarction in von Willebrand disease: characteristics and outcomes.

ABSTRACT:

Background

Von Willebrand disease (VWD) is the most common inherited bleeding disorder. As treatments have improved prognosis of VWD, age-related diseases, including acute myocardial infarction (AMI), have become more prevalent. The treatment of AMI includes antithrombotic therapies, which increase the risk of bleeding. Current guidelines suggest weighing risks/benefits of antithrombotic therapy in patients with VWD. However, data to inform these discussions are lacking.

Objective

To characterize outcomes of patients with VWD after AMI.

Methods

We conducted a retrospective cohort study utilizing the National Readmissions Database of patients with and without VWD admitted with AMI in 2017 and 2018. Primary outcomes were 90-day any-cause, bleeding-related, and arterial

SUBMITTER: Leiva O 

PROVIDER: S-EPMC10558305 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature