Cobalt-catalyzed alkene hydrogenation by reductive turnover.

ABSTRACT: Earth abundant metal catalysts hold advantages in cost, environmental burden and chemoselectivity over precious metal catalysts. Differences in reactivity for a given metal center result from ligand field strength, which can promote reaction through either open- or closed-shell carbon intermediates. Herein we report a simple protocol for cobalt-catalyzed alkene reduction. Instead of using an oxidative turnover mechanism that requires stoichiometric hydride, we find a reductive turnover mechanism that requires stoichiometric proton. The reaction mechanism appears to involve coordination and hydrocobaltation of terminal alkenes.

SUBMITTER: van der Puyl V 

PROVIDER: S-EPMC10573012 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature