Humoral immune response to SARS-CoV-2 and endemic coronaviruses in urban and indigenous children in Colombia.

ABSTRACT:

Background

Although anti-SARS-CoV-2 humoral immune responses and epidemiology have been extensively studied, data gaps remain for certain populations such as indigenous people or children especially in low- and middle-income countries. To address this gap, we evaluated SARS-CoV-2 seroprevalence and humoral immunity towards the parental B.1 strain, local SARS-CoV-2 variants, and endemic coronaviruses in children from Colombia from March to April 2021.

Methods

We performed a cross-sectional seroprevalence study with 80 children from Bogotá and expanded our analysis by comparing results with an independent observational study of 82 children from the Wiwa community living in the north-eastern Colombian territories. Antibody IgG titers towards SARS-CoV-2 and the endemic coronavir

SUBMITTER: Fernandez Villalobos NV 

PROVIDER: S-EPMC10589283 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature