Irisin and Cardiometabolic Disorders in Obesity: A Systematic Review.

ABSTRACT:

Background

Overweight and obesity are global health issues, impacting a significant portion of young adults. Obesity is a complex condition influenced by genetics and environmental factors, leading to increased susceptibility to cardiovascular diseases (CVDs), hypertension, dyslipidemia, and insulin resistance. Irisin, a protein derived from the cleavage of fibronectin type III domain-containing protein 5, may have relationship with these cardiometabolic diseases.

Objective

This systematic review aims to examine the relationship between serum irisin levels and obesity, particularly in individuals predisposed to cardiovascular risk factors.

Methods

A thorough literature search was conducted in multiple databases, including "Science Direct," "Scopus," "PubMed," and "Lil

SUBMITTER: Pinho-Jr JDS 

PROVIDER: S-EPMC10602702 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature