Does month of birth influence colorectal cancer prognosis?

ABSTRACT:

Purpose

The main aim of this study was to identify a possible association between month of birth of colorectal cancer (CRC) patients and overall survival (OS) or disease-free survival (DFS).

Methods

This observational study included all consecutive adult patients diagnosed with CRC undergoing oncological surgery from January 2005 to December 2019 with a minimum follow-up of 10 years. The outcome variables were locoregional recurrence, death due to cancer progression, OS and DFS. Non-supervised learning techniques (K-means) were conducted to identify groups of months with similar oncologic outcomes. Finally, OS and DFS were analysed using Kaplan-Meier and Cox regression tests. The model was calibrated with resampling techniques and subsequently a cross-validation was performe

SUBMITTER: Martin-Arevalo J 

PROVIDER: S-EPMC10602963 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature