Ontology highlight
ABSTRACT:
SUBMITTER: Chen YH
PROVIDER: S-EPMC10618599 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Chen Yi-Hsien YH Connelly Jon P JP Florian Colin C Cui Xiaoxia X Pruett-Miller Shondra M SM
Disease models & mechanisms 20231023 10
Cell lines are indispensable models for modern biomedical research. A large part of their usefulness derives from the ability of a cell line to proliferate over multiple passages (often indefinitely), allowing multiple experiments to be performed. However, over time, cell line identity and purity can be compromised by human errors. Cross-contamination from other cell lines and complete misidentification are both possible. Routine cell line authentication is a necessary preventive measure and has ...[more]