The impact of universal induction therapy on early hospital readmission of kidney transplant recipients.

ABSTRACT:

Background

Early hospital readmission (EHR) is associated with worse outcomes. The use of anti-thymocyte globulin (rATG) induction therapy is associated with increased efficacy in preventing acute rejection, although safety concerns still exist.

Methods

This retrospective single-center study compared the incidence, causes of EHR, and one-year clinical outcomes of patients receiving a kidney transplant between August 18, 2011 and December 31, 2012 (old era), in which only high-risk patients received 5 mg/kg rATG, with those transplanted between August 18, 2014 and December 31, 2015 (new era), in which all patients received a single 3 mg/kg dose of rATG.

Results

There were 788 patients from the Old Era and 800 from the New Era. The EHR incidence in the old era patients

SUBMITTER: Tavares MG 

PROVIDER: S-EPMC10627129 | biostudies-literature | 2023 Apr-Jun

REPOSITORIES: biostudies-literature