Determinants of Aortic Stenosis Progression in Bicuspid and Tricuspid Aortic Valves.

ABSTRACT:

Background

Bicuspid aortic valve (BAV) is associated with a faster progression of aortic stenosis (AS). Whether the determinants of AS progression are the same or different in patients with BAV vs tricuspid aortic valve (TAV) is unknown. The aim of this study was to identify the factors associated with the progression of AS in patients with BAV vs patients with TAV.

Methods

Patients with AS were prospectively recruited in the Metabolic Determinants of the Progression of Aortic Stenosis (PROGRESSA) study (ClinicalTrials.gov Identifier: NCT01679431). The haemodynamic progression rate of AS was assessed by the annualized progression rate of peak aortic jet velocity (V_peak). Univariable and multivariable linear regression analyses were used to identify the factors ass

SUBMITTER: Shen M 

PROVIDER: S-EPMC10642113 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature